2017

Abida Naemat, Faris Sinjab, Alison McDonald, Andy Downes, Alistair Elfick,Hany M. Elsheikha, Ioan Notingher, "Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging" J Raman Spectroscopy 2017 in press 


Dustin Shipp, Faris Sinjab, Ioan Notingher, “Raman spectroscopy: Techniques and applications in the life sciences”, Advances in Optics and Photonics, 2017 9(2), pp 315-428


Zhiyu Liao, Faris Sinjab, Amy Nommeots-Nomm, Julian Jones, Laura Ruiz-Cantu, Jing Yang, Felicity Rose, and Ioan Notingher, Feasibility of spatially-offset Raman spectroscopy for in-vitro and in-vivo monitoring mineralisation of bone tissue-engineering scaffolds, Anal Chem 2017 89 (1), pp 847–853.


Faris Sinjab, Giovanna Sicilia, Dustin Shipp, Maria Marlow, and Ioan Notingher, “Label-free Raman hyperspectral imaging of single cells cultured on polymer substrates”, Appl. Spectrosc. 2017 DOI: 10.1177/0123456789123456 (OPEN ACCESS)


Giuseppe Mazza, Walid Al-Akkad, Andrea Telese, Lisa Longato, Luca Urbani, Benjamin Robinson, Andrew Rennie Hall, Kenny Kong, Luca Frenguelli, Giusi Marrone, Oliver Willacy, Mohsen Shaeri, Massimo Malago, Janet Gilbertson, Nigel Rendel, Graham Taylor, Kevin Moore, David Hughes, Ioan Notingher, Gavin Jell, Armando Del Rio Hernandez, Paolo De Coppi, Krista Romboutsand Massimo Pinzani “Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization”, Sci Rep 2017  7, 5534 (OPEN ACCESS)



2016

Zhiyu Liao, Faris Sinjab, Graham Gibson, Miles Padgett, Ioan Notingher, “DMD-based software-configurable spatially-offset Raman spectroscopy for spectral depth-profiling of optically turbid samples”, Optics Express, 2016 24(12), 12701-12712. (OPEN ACCESS)


Faris Sinjab, Kenny Kong, Graham Gibson, Sandeep Varma, Hywel Williams, Miles Padgett, and Ioan Notingher, "Tissue diagnosis using power-sharing multifocal Raman micro-spectroscopy and auto-fluorescence imaging", Biomed Opt Express 2016 , 7(8) 2993-3006. (OPEN ACCESS)


Abida Naemat, Hany M. Elsheikha, Radu A. Boitor, Ioan Notingher, “Tracing amino acid exchange during host-pathogen interaction by combined stable-isotope time-resolved Raman spectral imaging”, Scientific Reports 6, 20811; doi: 10.1038/srep20811 (2016). (OPEN ACCESS)


Claire S. Sweetenham, Richard A. J. Woolley, Ioan Notingher, "In-situ fabrication of gold nanoparticle functionalized probes for tip-enhanced Raman spectroscopy by dielectrophoresis," J. Nanophoton. 10(3), 030502 (2016) (OPEN ACCESS)


Quynh, LM, Nam, NH, Kong, K, Nhung, NT, Notingher, I, Henini, M, Luong, NH, Surface-Enhanced Raman Spectroscopy Study of 4-ATP on Gold Nanoparticles for Basal Cell Carcinoma Fingerprint Detection, Journal Electronic Materials 2016, 45: 2563-2568


Radu Boitor, Faris Sinjab, Stephanie Strohbuecker, Virginie Sottile, Ioan Notingher, "Towards quantitative molecular mapping of cells by Raman microscopy: using AFM for decoupling molecular concentration and cell topography", Faraday Discussions 2016, 187, 199 – 212, DOI: 10.1039/C5FD00172B  (OPEN ACCESS)



2015

Kenny Kong, Catherine Kendall, Nicholas Stone, Ioan Notingher, “Raman spectroscopy for medical diagnostics - from in-vitro biofluid assays to in-vivo cancer detection” Adv. Drug Deliv. Rev. (2015) 89, 121–134. (OPEN ACCESS) 


Adrian Ghita, Flavius C. Pascut, Virginie Sottile, Chris Denning, Ioan Notingher, Applications of Raman micro-spectroscopy to stem cell technology: label-free molecular discrimination and monitoring of cell differentiation, EPJ-Techniques and Instrumentation 2015, 2:6 (OPEN ACCESS)


Sho Takamori, Kenny Kong, Sandeep Varma, Iain Leach, Hywel Williams, and Ioan Notingher, "Optimization of Multimodal Spectral Imaging for Assessment of Resection Margins during Mohs Micrographic Surgery of Basal Cell Carcinoma" Biomed Opt. Express, Vol. 6 (1) pp. 98–111 (2015) (OPEN ACCESS)


Abida Naemat, Hany M. Elsheikha, Alaa Al-sandaqchi, Kenny Kong, Adrian Ghita and Ioan Notingher, Analysis of interaction between the apicomplexan protozoan Toxoplasma gondii and host cells using label-free Raman Spectroscopy, Analyst 2015, 140, 756-764



2014 

Kenny Kong, Fazliyana Zaabar, Emad Rakha, Ian Ellis, Alexey Koloydenko,  Ioan Notingher, " Towards intra-operative diagnosis of tumours during breast conserving surgery by selective-sampling Raman micro-spectroscopy", Phys. Med. Biol. 59 (2014) 6141–6152 (OPEN ACCESS)


Adrian Ghita, Flavius Pascut, Virginie Sottile, Ioan Notingher, "Monitoring the mineralisation of bone nodules in-vitro by space- and time-resolved Raman micro-spectroscopy", Analyst 2014,139, 55-58. 


Faris Sinjab, Georgi Bondakov, Ioan Notingher, “Co-localised Raman and force spectroscopy reveals the roles of hydrogen bonds and π-π interactions in defining the mechanical properties of diphenylalanine nano- and micro-tubess”, Appl. Phys. Lett. 2014, 104, 251905.


Kenny Kong, Christopher J. Rowlands, Sandeep Varma, William Perkins, Iain H. Leach, Alexey A. Koloydenko, Alain Pitiot, Hywel C. Williams and Ioan Notingher, “Increasing the speed of tumour diagnosis during surgery with selective scanning Raman microscopy” J Molec Struct, 2014, 1073, 58-65. (OPEN ACCESS)


2013 

Kenny Kong, Christopher J. Rowlands, Sandeep Varma, William Perkins, Iain H. Leach, Alexey A. Koloydenko, Hywel C. Williams and Ioan Notingher, “Diagnosis of tumours during tissue conserving surgery with integrated auto- fluorescence and Raman scattering microscopy”, PNAS 2013, 110 (38), 15189-15194. doi/10.1073/pnas.1311289110. (OPEN ACCESS)


Flavius C Pascut, Andrew Downes, Ioan Notingher, “Raman Spectroscopy in regenerative medicine”, in “Optical Techniques in Regenerative Medicine. Edited by Stephen P. Morgan, Felicity R. Rose, and Steve Matcher © 2012 CRC Press/Taylor & Francis Group, LLC. ISBN: 978-1-4398-5495-2 


Flavius C Pascut, Spandan Kalra, Vinoj George, Nathan Welch, Chris Denning, Ioan Notingher “Non-invasive label-free monitoring the cardiac differentiation of human embryonic stem cells in-vitro by Raman spectroscopy”, Biochim. Biophys. Acta 1830 (2013), pp. 3517-3524 


2012 

Kenny Kong, Christopher J. Rowlands, Hany Elsheikha, Ioan Notingher, “Towards fast label-free molecular analysis of live cellular parasitology by selective scanning Raman micro-spectroscopy”, Analyst 2012, 137 (18), 4119 - 4122. (OPEN ACCESS)


Banyat Lekprasert, Vladimir Korolkov, Alexandra Falamas, Vasile Chis, Clive J. Roberts, Saul J. B. Tendler, Ioan Notingher “Investigations of the supramolecular structure of individual diphenylalanine nanotubes by polarized Raman micro-spectroscopy” Biomacromolecules 2012, 13(7) 2181–2187 


F. Sinjab, B. Lekprasert, R. Woolley, C. J. Roberts, S. J. B. Tendler, I. Notingher, “Near-field Raman spectroscopy of biological nanomaterials by in-situ laser-induced synthesis of TERS tips” Optics Letters, (2012), 37(12) 2256–2258


Adrian Ghita, Flavius C Pascut, M Mather, V Sottile, I Notingher, “Cytoplasmic RNA in undifferentiated neural stem cells: a potential label-free Raman spectral marker for assessing the undifferentiated status” Analytical Chemistry 2012, 84 (7), pp 3155–3162 


Christopher J Rowlands, Sandeep Varma, William Perkins, Iain Leach, Hywel Williams, Ioan Notingher “Rapid acquisition of Raman spectral maps through minimal sampling: applications in tissue imaging”, J. Biophotonics (2012) 3, 220-229. 


2011

Claire S. Sweetenham, Marta Larraona-Puy, Ioan Notingher “Simultaneous SERS and AFM for label-free physicochemical analysis of lipid bilayers” Applied Spectroscopy, (2011) 65(12), 1387-1392. 


Claire S. Sweetenham, Ioan Notingher, “Combined AFM-Raman mapping of electric field enhancement and SERS hot-spots for nanosphere lithography substrates”, J. Nanophotonics (2011), 5, 059504. (OPEN ACCESS)


Flavius C. Pascut, Huey T. Goh, Vinoj George, Chris Denning, Ioan Notingher, “Towards label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells“ J. Biomed Opt. (2011) 16, 045002


Alina Zoladek, Flavius C. Pascut, Poulam Patel, Ioan Notingher, “Non-Invasive Time-Course Imaging of Apoptotic Cells by Confocal Raman Micro-Spectroscopy”, J Raman Spectrosc. (2011) 42, 251-258. 


Flavius C. Pascut, Huey T. Goh, Nathan Welch, Lee D. Buttery, Chris Denning, Ioan Notingher, “Non-invasive detection and imaging of molecular markers in live cardiomyocytes derived from human embryonic stem-cells”, Biophys. J. (2011) 100(1):251-259. (OPEN ACCESS)


S. Verrier, A. Zoladek, I. Notingher “Raman micro-spectroscopy as a non-invasive cell viability test”, in "Mammalian Cells Viability Methods", edited by M. Stoddart, series Methods in Molecular Biology (2011), 740: 179-189, Springer. 


2010 

B. Lekprasert, V. Sedman, C. J. Roberts, S. J. B. Tendler, and I. Notingher, “Non-destructive Raman and AFM measurement of molecular structure for individual diphenylalanine nanotubes” Opt. Lett. (2010), 35 (24), 4193-4195


Alina Bogumila Zoladek, Ramneek Kaur Johal, Samuel Garcia-Nieto, Flavius Pascut, Kevin Shakesheff, Amir Ghaemmaghami, Ioan Notingher, “Label-free molecular imaging of immunological synapses between dendritic and T-cells by Raman micro-spectroscopy”, Analyst (2010), 135, 3205 - 3212 


2009 

Marta Larraona-Puy, Adrian Ghita, Alina Zoladek, William Perkins, Sandeep Varma, Iain H. Leach, Alexey A. Koloydenko, Hywel Williams, Ioan Notingher “Development of Raman micro-spectroscopy for automated detection and imaging of Basal Cell Carcinoma”, J Biomed Opt. (2009) 14, 054031


2008 

E. Pauliac-Vaujour, A. Stannard, C.P. Martin, M.O. Blunt, I. Notingher, P.J. Moriarty, I. Vancea, U. Thiele “Fingering instabilities in dewetting nanofuids”, PRL, (2008) 100, 176102 


G. Jell, I. Notingher, O. Tsigkou, P. Notingher, J. M. Polak, L. L. Hench, M. M. Stevens, “Bioactive glass induced osteoblast differentiation: A non-invasive spectroscopic study”, J. Biomed. Mat. Res. (2008), 86A, 31-40. 


2007 

I Notingher, J Jones, “Characterisation of tissue engineering constructs by Raman spectroscopy and X-ray micro-computed tomography (μCT)”, in Advances in Tissue Engineering, Julia Polak ed, Imperial College Press., 2007 


I Notingher, “Non-invasive characterisation of living cells and tissue engineering scaffolds by Raman micro-spectroscopy”, in “TISSUE ENGINEERING USING CERAMICS AND POLYMERS” by A Boccaccini and J Gough Eds, Woodhead Publishing Ltd, 


I Notingher, “Raman spectroscopy cell-based biosensors”, Sensors (2007), 7, 1343-1358 (Special issue on Optical Biosensors) 


2006 

C. A. Owen, I. Notingher, R. Hill, M. M. Stevens, L. L. Hench, “Progress in Raman spectroscopy in the fields of tissue engineering, diagnostics and toxicological testing”, J. Mater. Sci. Mater. Med. 17 (2006), 1019-1023 


I Notingher, JJ. Blaker, V Maquet, LL Hench, AR Boccaccini, “Effect of Polymer Processing on the Degradation of 45S5 Bioglass®/Poly(lactic acid-co-glycolic acid) Composite Scaffolds for Tissue Engineering”, Asian J. Phys. 15 (2006), 221-230


C. Owen, J. Selvakumaran, I. Notingher, G. Jell, L. L. Hench, M. M. Stevens, “In-vitro evaluation of pharmaceuticals using Raman micro-spectroscopy”, J. Cell. Biochem, 99 (2006) 178-186


S.D. McLoughlin, R.J. Hand, N.C. Hyatt, W.E. Lee, I. Notingher, D.S. McPhail, J. Henderson. “The long term corrosion of glasses: analytical results after 32 years of burial at Ballidon”, Glass Technology 47 (2006) 59-67.  


I. Notingher, L.L. Hench, “Raman micro-spectroscopy: a non-invasive tool for studies of individual living cells in-vitro”, Exp Rev Med Dev, 3 (2006), 215-234.


2005 

I. Notingher, A. Elfick, “The Effect of Sample and Substrate Electric Properties on the Electric Field Enhancement at the Apex of SPM Nano-Tips”, J. Phys. Chem. B. 109 (2005), 15699-15706. 


2004 

I. Notingher, I. Bisson, A. E. Bishop, W. L. Randle, J. M. P. Polak, L. L. Hench, “In-Situ Monitoring of mRNA Translation in Embryonic Stem Cells During Differentiation In-Vitro”, Anal. Chem. 76 (2004), 3185-3193 


I. Notingher, C. Green, C. Dyer, E. Perkins, N. Hopkins, C. Lindsay, L.L. Hench, “Discrmination between ricin and sulphur mustard using a Raman spectroscopy Cell-Based Biosensor”, J. R. Soc. Interface 1(1)(2004), 79-90. 


I. Notingher, G. Jell, U. Lohbauer, V. Salih, L. L. Hench, “In-Situ Non-Invasive Discrimination Between Bone Cell Phenotypes Used in Tissue Engineering”, J. Cell. Biochem. 92 (2004), 1180-1192 


L. L. Hench, I. Notingher, “NovaTest: A Biophotonics System for Rapid In-Vitro Toxicity Testing”, Am. Cer. Soc. Bull. 83 (2004)


 J. E. Gough, I. Notingher, L. L. Hench, “Osteoblast attachment and mineralisation nodule formation on rough and smooth 45S5 bioglass monoliths”, J. Biomed. Mat. Res. 68A (2004), 640-650. 


I. Notingher, R. E. Imhof, “Mid-Infrared In-Vivo Depth-Profiling of Topical Chemicals on Skin”, Skin Res. Tech. 10 (2004), 113-121. 


I. Notingher, J. Selvakumaran, L. L. Hench “New Detection System for Toxic Agents Based on Continuous Spectroscopic Monitoring of Living Cells”, Biosensors and Bioelectronics 20 (2004), 780-789.


V. Maquet, A. R. Boccaccini, L. Pravata, I. Notingher, R. Jerome, “Porous poly(α-hydroxyacid)/Bioglass composite scaffolds for bone tissue engineering. I: preparation and in-vitro characterisation”, Biomaterials 25 (2004), 4185-4194.


D.C. Clupper, J.E. Gough, P.M. Embanga, I. Notingher, L.L. Hench, M.M. Hall, “Bioactive evaluation of 45S5 bioactive glass fibres and preliminary study of human osteoblast attachment, ”, J. Mater. Sci. Mater. Med. 15 (2004), 803-808 


2003 

J. J. Blaker, J. E. Gough, V. Maquet, I. Notingher, A. R. Boccaccini, “In vitro evaluation of novel bioactive composites based on Bioglass-filled polylactide foams for bone tissue engineering scaffolds”, J. Biomed. Mat. Res. 67A (2003), 1401-1411 


I. Notingher, R. E. Imhof, P. Xiao, F. C. Pascut, “Spectral Depth-Profiling of Arbitrary Surfaces by Thermal Emission Decay-Fourier Transform Infrared Spectroscopy”, Appl. Spectrosc. 57, 1494-1501 (2003) 


I. Notingher, S. Verrier, S. Haque, J. M. Polak, L. L. Hench, “Spectroscopic study of human lung epithelium cells (A549 cell line): living cells and cell death”, Biopolymers 72 (4) (2003), 230-240 


I. Notingher, A. R. Boccaccini, J. Jones, V. Maquet, L. L. Hench, “Applications of Raman Micro-Spectroscopy to the Characterisation of Bioactive Materials”, Mater. Charact. 49 (2003), 255-260 


A. R. Boccaccini, I. Notingher, V. Maquet, R. Jérôme, “Bioresorbable and Bioactive Composite Materials Based on Polylactide Foams Filled with and Coated by Bioglass® Particles for Tissue Engineering Applications”, J. Mater. Sci.-Mater. M. 14 (5) (2003), 443-450 


V. Maquet, A. R. Boccaccini, L. Pravata, I. Notingher, R. Jérôme, “Preparation, Characterisation and In Vitro Degradation of Bioresorbable and Bioactive Composites Based on Bioglass®-Filled Polylactide Foams”, J. Biomed. Mat. Res. 66A (2003), 335-346 


2002 

I. Notingher, S. Verrier, H. Romanska, A. E. Bishop, J. M. Polak, L. L. Hench, “In-situ characterization of living cells by Raman spectroscopy”, Spectrosc.-Int.J. 16 (2002), 43-51